Alpha-Fetoprotein (AFP)


Alpha-Fetoprotein (AFP) is normally produced during fetal and neonatal development by the liver, yolk sac and in small concentrations by the gastrointestinal tract. By the second year of life, AFP concentrations decrease rapidly, and thereafter only trace amounts are normally detected in serum. In general, normal adults have serum AFP concentrations of less than 10 ng/mL. Elevated AFP levels occur in several malignant diseases including hepatocellular carcinoma, testicular nonseminomatous origin, and occasionally of other entodermal origin.

AFP has also been used to detect early tumors in people at high risk for liver cancer. Studies of patients with large hepatic etastases or viral hepatitis also indicate slightly elevated or persistent AFP values. In areas where liver cancer is common, the use of AFP tests for screening has resulted in the detection of many tumors at an earlier stage. Detection of elevated AFP levels can also be used in the detection of fetal open neural tube defects.

The AFP One Step Rapid Test utilizes a combination of colloidal gold conjugate and monoclonal antibodies to selectively detect elevated levels of AFP.

Cassette Buffer Dropper 2
Product NameSpecimenFormatSensitivityCatalog No.Certifications
Alpha-Fetoprotein Rapid TestSerum/PlasmaCassette20 ng/mlGEAFP-302aCE Marked, Not For US Market
Uncut SheetGEAFP-304aCE Marked, Not For US Market
Whole Blood/Serum/PlasmaCassette20 ng/mlGEAFP-402aCE Marked, Not For US Market
Uncut SheetGEAFP-404aCE Marked, Not For US Market