Heart Fatty Acid-Binding Protein (h-FABP) Rapid Detection Kit
Heart Fatty Acid-Binding Protein (h-FABP) Rapid Test is a rapid visual immunoassay for the qualitative presumptive detection of cardiac Heart fatty acid-binding protein (h-FABP) in human whole blood, serum, or plasma specimens. This kit is intended to be used as a screening method to aid in the diagnosis of myocardial infarction (MI).
Heart-type fatty acid binding protein (h-FABP) is known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. Heart-type Fatty Acid-Binding Protein (H-FABP) is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. h-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours after the onset acute chest pain. The diagnostic potential of the biomarker H-FABP for heart injury was discovered in 1988 by Professor Jan Glatz (Maastricht, Netherlands) h-FABP is 20 times more specific to cardiac muscle than myoglobin, it is found at 10-fold lower levels in skeletal muscle than heart muscle and the amounts in the kidney, liver and small intestine are even lower again.
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