Procalcitonin (PCT) Rapid Detection Kit

The Procalcitonin Rapid Test Cassette (Whole Blood/Serum/Plasma) is a rapid test that qualitative detects the presence of Procalcitonin in whole blood, plasma or serum specimens at the sensitivity of 0.5 ng/mL. The test utilizes a combination of monoclonal antibodies to selectively detect elevated levels of Procalcitonin in whole blood, plasma or serum.

 

The Procalcitonin (PCT) is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin, Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock.

Features

  • Two band results for simple interpretation

  • Room temperature storage or refrigerated (2-30⁰C)

  • Internal control included

  • The appearance of control line serves as a procedural control

Specifications

  • Cut-off(s): See ordering information below

  • Sensitivity: 93.6%

  • Specificity: 96.3%

  • Specimen: Whole Blood, Serum, Plasma

  • Time to Results: 10 minutes

  • Shelf Life: 24 months from the date of manufacture

Ordering Information

ITEM CODE
DESCRIPTION
FORMAT
SPECIMEN
UOM
GDPCT-402a
Procalcitonin Rapid Test: 0.5 ng/mL
Cassette
Whole Blood/ Serum/Plasma
25 Tests/Kit
GDPCT-T401a
Procalcitonin Rapid Test: 0.5-2-10 ng/mL
Strip
Whole Blood/ Serum/Plasma
50 Tests/Kit
GDPCT-T402a
Procalcitonin Rapid Test: 0.5-2-10 ng/mL
Cassette
Whole Blood/ Serum/Plasma
25 Tests/Kit

Sources:

1. Müller B. et al.: Calcitonin precursors are reliable markers of sepsis in medical intensive care unit. Crit. Care Med. 2000, 28(4): 977-983

2. Harbarth S. et al.: Diagnostic value of procalcitonin, inter- leukin-6 and interleukin 8 in critically ill patients admitted with suspected sepsis. Am. J. Resp. Crit. Care Med. 2001, 164: 396-402

3. Brunkhorst F.M. et al.: Procalcitonin for early diagnosis and differentiation of SIRS, sepsis, severe sepsis and septic shock. Intensive Care Med. 2000, 26(suppl.2): 148-152

4. Meisner M.: Procalcitonin (PCT) – A new, innovative infection parameter. Biochemical and clinical aspects. Thieme Stuttgart, New York 2000, ISBN: 3-13-105503-0

5. Meisner M. et al.: Procalcitonin – Influence of temperature, storage, anticoagulation and arterial or venous asservation of blood samples on procalcitonin concentrations. Eur J Clin Chem Clin Biochem 1997, 35 (8): 597-601

6. American College of Chest Physicians/Society of Critical Care Medicine: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992, 20: 864-874

7. Morgenthaler N. et al.: Detection of procalcitonin (PCT) in healthy controls and patients with local infection by a sensitive ILMA. Clin Lab. 2002. 48(5-6): 263-70

8. Meisner Metal.:Clinical experiences with a new semi-quantitative solid phase immunoassay for rapid measurement of procalcitonin. Clin. Chem. Lab. Med. 2000, 38(10): 989-995

9. Chiesa C, Panero A, Rossi N, Stegagno M, De Giusti M, Osborn JF, Pacifico L. Clin Infect Dis (1998), 26: 664-672: Re-liability of Procalcitonin Concentrations for the Diagnosis of Sepsis in Critically III Neonates