Toxoplasmosis Antibody Rapid Detection Kit

Toxo Rapid Test Cassette is a lateral flow immunochromatographic assay for the rapid, qualitative and differential detection of IgG and IgM antibodies to Toxoplasma gondii in human whole blood, serum or plasma.

 

Toxoplasmosis is a food borne illness caused by Toxoplasma gondii, a protist Pathogen. The ubiquitous intracellular living parasite is spread worldwide. Typical for sporocytes is the “flip-flop” between sexual (which only takes place in cats, the final host) and asexual reproduction. The Infection is often highest in areas of the world that have hot, humid climates and lower altitudes. The mean source of infection is direct contact with cat feces or from eating undercooked meats. Toxoplasmosis is not passed from person-to-person, except in instances of mother-to-child (congenital) transmission and blood transfusion or organ transplantation. Toxoplasmosis generally presents with mild symptoms in immunocompetent individuals, but women newly infected with Toxoplasma during pregnancy and anyone with a compromised immune system should be aware that toxoplasmosis can have severe consequences for them. Acute toxoplasmosis in pregnant women can result in miscarriage, poor growth, early delivery or stillbirth. IgG and IgM antibodies to Toxoplasma can be detected within 2-3 weeks after exposure. IgG remains positive, but the antibody level drops overtime.

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Sources:

1. Diagnosis of congenital toxoplasmosis: prenatal and neonatal evaluation of methods used in Toulouse University Hospital and incidence of congenital toxoplasmosis. Bessières MH, Berrebi A, Cassaing S, Fillaux J, Cambus JP, Berry A, Assouline C, Ayoubi JM, Magnaval JF.

2. Dynamic Imaging of CD8(+) T cells and dendritic cells during infection with Toxoplasma gondii. John B, Harris TH, Tait ED, Wilson EH, Gregg B, Ng LG, Mrass P, Roos DS, Dzierszinski F, Weninger W, Hunter CA.

3. Congenital toxoplasmosis: evaluation of serological methods for the detection of anti-Toxoplasma gondii IgM and IgA antibodies. Rodrigues IM, Castro AM, Gomes MB, Amaral WN, Avelino MM. Mem Inst Oswaldo Cruz. 2009 May; 104(3):434-40.

4. Seroprevalence of Toxoplasma gondii infection and characteristics of seropositive patients in general hospitals in Daejeon, Korea. Shin DW, Cha DY, Hua QJ, Cha GH, Lee YH. Korean J Parasitol. 2009 Jun;47(2):125-30. Epub 2009 May 27, D.C.

5. Johnson P.C. Testing for Syphilis. Dermatologic Clinic (1994); 12 Jan: 9-17.

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