Fetal Fibronectin (fFN) Rapid Detection Kit

The fetal fibronectin (fFN) rapid test is a visually interpreted, qualitative immunochromatographic test device for detection of fFN in vaginal secretions during pregnancy, which is a special protein that literally holds your baby in place in the womb. The test is intended for professional use to help diagnose the rupture of fetal membranes (ROM) in pregnant women.

Fetal fibronectin (fFN) is a “glue-like” protein that bonds your developing baby to your uterus. Fetal fibronectin is detectable in vaginal secretions in the very beginning of pregnancy, when this bond is first forming, and then again at the end of pregnancy, when your body is getting ready to deliver your baby. fFN is a special protein that literally holds your baby in place in the womb. After the 35th week of pregnancy, it begins to break down naturally, and is detectable. If your body is getting ready to give birth prematurely, fFN may be detected before week 35. From weeks 22 to 35 in your pregnancy, there should be very little fFN detectable. fFN can often be detected before other symptoms of preterm labor, such as contractions and changes in cervical length. Doctors may use a combination of signs and symptoms when deciding the best course of action to take in relation to your pregnancy.

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Sources:

1. Wadell, G. Laboratory Diagnosis of Infectious Diseases: Principles and Practices. New York: Springer-Verlag, Volume II, 1988: 284-300.
2. WILHELMI I, ROMAN E, SANCHEZ-FAUQUIER A. Viruses causing gastroenteritis. Clin Microbiol Infect. April. 2003, vol.9:247-262
3. Cubitt, WD (1982) Rotavirus Infection: An Unexpected Hazard in Units Caring for the Elderly. Geriatric Medicine Today 1: 33-38
4. Erdemoglu and Mungan T. Significance of detecting insulin-like growth factor binding protein-1 in cervicovaginal secretions: Comparison with nitrazine test and amoniotic fluid volume assessment. Acta Obstet Gynecol Scand (2004) 83: 622-626

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